Cytodiagnosis of obstructive jaundice

Obstructive Jaundice

Obstructive Jaundice

Introduction Neonatal cholestasis is defined as prolonged elevation of serum levels of conjugated bilirubin beyond the first 14 days of life. Neonatal hyperbilirubinaemia is usually physiologic, unconjugated, and self-limited. Only 2–15% of neonates remain jaundiced past 2 weeks of life, and just 0.2–0.4% have cholestatic jaundice from either intrahepatic cholestasis or structural abnormalities...

Effects of obstructive jaundice

Obstructive jaundice is a common surgical problem that occurs when there is blockage of the passage of conjugated bilirubin from liver to intestine. In most benign biliary diseases, jaundice is intermittent and incomplete. Only a few diseases (e.g. primary sclerosing cholangitis) result in persistent obstructive jaundice, or even in biliary cirrhosis and portal hypertension, and most cases are ...

Endotoxaemia in Obstructive Jaundice

Surgical procedures in patients with obstructive jaundice are associated with significant morbidity and mortality1. This is due, to a large extent, to the development of postoperative complications such as sepsis, bleeding disorders and renal failure24. Clinical and experimental studies have suggested several aetiological factors for these complications including hypotension, impaired nutrition...

Intrahepatic Obstructive Jaundice

OBs-mucTivF jaundice is amenable to surgical treatment when the obstruction is extrahepatic. In recent years it has been recognised that the obstruction may be intrahepatic and the complete picture of obstructive jaundice may be seen without obstruction of the main bile ducts. It is important to differentiate between intrahepatic anid extrahepatic cholestasis in order to avoid unnecessary surgi...